SCHEMBL29675227

SCHEMBL29675227

O=C(O)CCC(=O)Nc1ccc(-c2nc3ccccc3[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.78
MMP13 P45452 3/20 0.78
MMP9 P14780 2/20 0.78
MMP8 P22894 2/20 0.78
PKM P14618 1/20 0.72
HPSE Q9Y251 1/20 0.70
ALDH1A1 P00352 3/20 0.69
KDM4E B2RXH2 2/20 0.69
MEN1 O00255 2/20 0.69
NPC1 O15118 2/20 0.69
MAPT P10636 2/20 0.69
HPGD P15428 2/20 0.69
RAB9A P51151 2/20 0.69
KMT2A Q03164 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
TP53 P04637 1/20 0.69
POLB P06746 1/20 0.69
HSD17B10 Q99714 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15702637 1.00 MMP2 (0.78) MMP2MMP13MMP9MMP8PKM
SCHEMBL8820296 0.90 MMP2 (0.82) MMP2MMP13MMP9MMP8HPSE
SCHEMBL8818644 0.89 MMP2 (0.80) MMP2MMP13MMP9MMP8HPSE
SCHEMBL8820321 0.89 MMP2 (0.80) MMP2MMP13MMP9MMP8HPSE
SCHEMBL8820325 0.89 MMP2 (0.80) MMP2MMP13MMP9MMP8HPSE
SCHEMBL8870051 0.89 MMP2 (0.80) MMP2MMP13MMP9MMP8HPSE
SCHEMBL31032564 0.88 PKM (0.73) MMP2MMP13MMP9MMP8PKM
SCHEMBL15702613 0.88 PKM (0.73) MMP2MMP13MMP9MMP8PKM
SCHEMBL15705308 0.88 PKM (0.66) MMP2MMP13MMP9MMP8PKM
SCHEMBL15702612 0.87 KDM4E (0.87) MMP2MMP13MMP9MMP8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642749-A1 CROP NUTRITION AND FORTIFICATION COMPOSITION Bhukhanwala, Komal (IN) 2025-11-05 EP disclosed
US-20250255936-A1 CONTROLLED RELEASE FORMULATIONS OF OCTREOTIDE ENDO OPERATIONS LIMITED (IE) 2025-08-14 US disclosed
US-20240391989-A1 METHODS FOR INHIBITING MYOSTATIN ACTIVATION BY ADMINISTERING ANTI-PRO/LATENT MYOSTATIN ANTIBODIES SCHOLAR ROCK, INC. 2024-11-28 US disclosed
US-12072797-B2 Memory system and non-transitory computer readable recording medium KIOXIA CORPORATION (JP) 2024-08-27 US disclosed
US-20240261245-A1 METHODS OF TREATING CANCERS HAVING A DEREGULATED NRF2/KEAP1 PATHWAY UNIV NEW YORK (US) 2024-08-08 US disclosed
WO-2024142112-A1 CROP NUTRITION AND FORTIFICATION COMPOSITION BHUKHANWALA KOMAL (IN) 2024-07-04 WO disclosed
US-20230281118-A1 MEMORY SYSTEM AND NON-TRANSITORY COMPUTER READABLE RECORDING MEDIUM KIOXIA CORPORATION (JP) 2023-09-07 US disclosed
US-11687448-B2 Memory system and non-transitory computer readable recording medium KIOXIA CORPORATION (JP) 2023-06-27 US disclosed
US-20230111088-A1 ANTI-DRUG ANTIBODY ASSAY HOFFMANN LA ROCHE (US) 2023-04-13 US disclosed
US-20220253381-A1 MEMORY SYSTEM AND NON-TRANSITORY COMPUTER READABLE RECORDING MEDIUM KIOXIA CORP (JP) 2022-08-11 US disclosed
US-11347637-B2 Memory system and non-transitory computer readable recording medium KIOXIA CORPORATION (JP) 2022-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250255936-A1 CONTROLLED RELEASE FORMULATIONS OF OCTREOTIDE GHSR, VIPR1, VIPR2 MMP2 4062/4885MMP13 3138/4885MMP9 4687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.