Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343856 | 0.86 | MAPK1 (0.40) | ACACBMAPK1ADORA2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29676873 | 0.85 | MAPK1 (0.39) | ACACBMAPK1ADORA2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18793899 | 0.84 | MAPK1 (0.46) | ACACBMAPK1 | |
| SCHEMBL24925804 | 0.84 | MAPK1 (0.44) | ACACBMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL29676835 | 0.82 | MAPK1 (0.38) | ACACBMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL29676186 | 0.81 | ACACB (0.48) | ACACBMAPK1CYP3A4ADORA2AADORA1 | |
| SCHEMBL29675858 | 0.79 | NPSR1 (0.39) | ACACBMAPK1ADORA2AALDH1A1LMNA | |
| SCHEMBL18765710 | 0.77 | KCNA5 (0.42) | ACACBMAPK1CYP3A4ADORA2A | |
| SCHEMBL29675917 | 0.76 | ADRB1 (0.49) | ACACBMAPK1ALDH1A1 | |
| SCHEMBL29676282 | 0.73 | TRPV3 (0.47) | ACACBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |