Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676136 | 0.85 | MAPK1 (0.38) | PGK1PGK2MAPK1SMN1; SMN2ADORA2A | |
| SCHEMBL29675917 | 0.81 | ADRB1 (0.49) | ACACBTGFBR1MAPK1ALDH1A1 | |
| SCHEMBL29675906 | 0.80 | ACACB (0.47) | NPSR1ACACBTGFBR1TGFBR2CTRB1 | |
| SCHEMBL29675377 | 0.79 | ACACB (0.46) | NPSR1ACACBLMNAUSP2MAPK1 | |
| SCHEMBL18765710 | 0.79 | KCNA5 (0.42) | ACACBMAPK1ADORA2A | |
| SCHEMBL29676282 | 0.75 | TRPV3 (0.47) | ACACBADORA2A | |
| SCHEMBL24015882 | 0.75 | ALDH1A1 (0.44) | LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24015880 | 0.75 | ALDH1A1 (0.44) | LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19322907 | 0.75 | ALDH1A1 (0.44) | LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27284194 | 0.73 | TRPV3 (0.44) | ACACBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |