Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676228 | 0.89 | MAPK1 (0.42) | MAPK1MEN1KMT2AGFERLMNA | |
| SCHEMBL29675407 | 0.83 | MEN1 (0.56) | MEN1KMT2AGFERPRCPHTR1A | |
| SCHEMBL18794507 | 0.81 | ALDH1A1 (0.43) | HTR1ALMNACTSLCTSBCTSS | |
| SCHEMBL23343854 | 0.77 | MAPK1 (0.40) | MAPK1MEN1KMT2ALMNACTSK | |
| SCHEMBL31036979 | 0.76 | HTT (0.49) | MEN1KMT2ALMNAACACB | |
| SCHEMBL29675587 | 0.75 | MAPK1 (0.42) | MAPK1GFERLMNAACACB | |
| SCHEMBL29676031 | 0.75 | MAPK1 (0.42) | MAPK1ACACB | |
| SCHEMBL29675856 | 0.71 | MEN1 (0.55) | MAPK1MEN1KMT2AGFERLMNA | |
| SCHEMBL20738607 | 0.69 | MAPK1 (0.44) | MAPK1LMNACTSLCTSBCTSS | |
| SCHEMBL29675519 | 0.69 | MAPK1 (0.43) | MAPK1HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |