Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.43 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675364 | 0.81 | HTR3E (0.46) | ACACBMAPK1CHRNA7 | |
| SCHEMBL18765485 | 0.81 | HTR3E (0.46) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675744 | 0.81 | AOC3 (0.45) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675453 | 0.81 | SHMT2 (0.47) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675445 | 0.81 | ACACB (0.43) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675519 | 0.78 | MAPK1 (0.43) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675721 | 0.78 | PIM2 (0.45) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675686 | 0.78 | PIM2 (0.45) | ACACBMAPK1CHRNA7 | |
| SCHEMBL29675797 | 0.77 | ACACB (0.49) | ACACBMAPK1 | |
| SCHEMBL29675879 | 0.76 | ACACB (0.46) | ACACBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |