Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595500 | 0.91 | LPL (0.38) | LPLLIPGGFERBACE1ROCK1 | |
| SCHEMBL31222957 | 0.91 | LPL (0.38) | LPLLIPGGFERBACE1ROCK1 | |
| SCHEMBL12470951 | 0.88 | DRD2 (0.45) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL20612387 | 0.80 | BRD9 (0.39) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL29676875 | 0.80 | PARP10 (0.54) | LPLLIPGBACE1 | |
| SCHEMBL2052209 | 0.80 | PARP10 (0.54) | LPLLIPGBACE1 | |
| SCHEMBL21382549 | 0.79 | KDM4E (0.43) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL17042127 | 0.79 | CA9 (0.50) | LPLLIPGSMN1; SMN2BACE1CA9 | |
| SCHEMBL31371681 | 0.77 | ASIC3 (0.46) | LPLLIPGDRD2 | |
| SCHEMBL17948747 | 0.77 | ASIC3 (0.46) | LPLLIPGDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307415-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | JIANGSU SIMCERE PHARMACEUTICAL CO., LTD. (CN) | 2024-09-19 | — | — | US | disclosed |
| EP-4365183-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Jiangsu Simcere Pharmaceutical Co., Ltd. (CN) | 2024-05-08 | — | — | EP | disclosed |
| CN-117580849-A | Steroid compound, pharmaceutical composition and application thereof | 江苏先声药业有限公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023186072-A1 | LIGAND-DRUG CONJUGATE AND USE THEREOF | 江苏先声药业有限公司 | 2023-10-05 | — | — | WO | disclosed |
| WO-2022268176-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 江苏先声药业有限公司 | 2022-12-29 | — | — | WO | disclosed |
| WO-2022268176-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 江苏先声药业有限公司 | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240307415-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | NR5A1, HSD17B7, CYP17A1 | LPL 1969/4885LIPG 2220/4885GFER 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.