Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 8/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26223112 | 0.94 | HTR2A (0.43) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL26222559 | 0.94 | HTR2A (0.43) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL17937004 | 0.93 | HTR2A (0.45) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL25013856 | 0.93 | HTR2A (0.45) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL30479875 | 0.93 | HTR2A (0.43) | HTR2ASSTR3FURINALDH1A1PDF | |
| SCHEMBL25247251 | 0.93 | HTR2A (0.43) | HTR2ASSTR3FURINALDH1A1PDF | |
| SCHEMBL17312917 | 0.92 | HTR2A (0.44) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL17902992 | 0.92 | ALDH1A1 (0.46) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL15528822 | 0.92 | HTR2A (0.47) | HTR2ASSTR3FURINSIRT5ALDH1A1 | |
| SCHEMBL15528820 | 0.92 | HTR2A (0.47) | HTR2ASSTR3FURINSIRT5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352348-B2 | Splicing modulator antibody-drug conjugates and methods of use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352348-B2 | Splicing modulator antibody-drug conjugates and methods of use | RBM17, RBM22, SF3B1 | HTR2A 3646/4885SSTR3 3242/4885FURIN 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.