SCHEMBL29678142

SCHEMBL29678142

CN(C)c1cccc2c(S(=O)(=O)N3CCC(CO)CC3)cccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.70
ATM Q13315 1/20 0.70
TGM2 P21980 5/20 0.54
HTR6 P50406 1/20 0.54
EPHX1 P07099 1/20 0.52
EPHX2 P34913 1/20 0.52
CA2 P00918 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
HIF1A Q16665 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GBA1 P04062 1/20 0.47
F2 P00734 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
EDNRA P25101 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25531 0.85 KMT2A (0.88) KMT2AATMTGM2HTR6EPHX1
SCHEMBL29437927 0.85 KMT2A (0.88) KMT2AATMTGM2HTR6EPHX1
SCHEMBL29678201 0.84 KMT2A (0.58) KMT2AATMTGM2HTR6EPHX1
SCHEMBL29238135 0.84 KMT2A (0.58) KMT2AATMTGM2HTR6EPHX1
SCHEMBL5650140 0.82 KMT2A (0.77) KMT2AATMTGM2HTR6CA2
SCHEMBL31033068 0.82 KMT2A (0.77) KMT2AATMTGM2HTR6CA2
SCHEMBL13713907 0.81 KMT2A (0.68) KMT2AATMTGM2HTR6EPHX1
SCHEMBL18138090 0.81 KMT2A (0.75) KMT2AATMTGM2HTR6CA2
SCHEMBL19856464 0.81 KMT2A (0.75) KMT2AATMTGM2HTR6CA2
SCHEMBL15934204 0.80 KMT2A (0.79) KMT2AATMTGM2HTR6CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685560-B Synthesis and application of phosphoramidite monomer containing piperidine skeleton and oligonucleotide 沈阳药科大学 2024-05-14 CN claimed
CN-114685560-A Synthesis and application of phosphoramidite monomer containing piperidine skeleton and oligonucleotide 沈阳药科大学 2022-07-01 CN claimed
CN-114685560-B Synthesis and application of phosphoramidite monomer containing piperidine skeleton and oligonucleotide 沈阳药科大学 2024-05-14 CN disclosed
CN-114685560-A Synthesis and application of phosphoramidite monomer containing piperidine skeleton and oligonucleotide 沈阳药科大学 2022-07-01 CN disclosed