Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973318 | 0.95 | BACE1 (0.46) | BACE1BACE2 | |
| SCHEMBL38650823 | 0.95 | BACE1 (0.44) | BACE1BACE2 | |
| SCHEMBL38656914 | 0.93 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29678374 | 0.88 | OPRM1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL38651067 | 0.86 | KISS1R (0.43) | BACE1BACE2 | |
| SCHEMBL31230203 | 0.81 | OPRM1 (0.60) | BACE1BACE2 | |
| SCHEMBL29678561 | 0.81 | CCKAR (0.51) | — | |
| SCHEMBL29678509 | 0.80 | NPY4R (0.60) | — | |
| SCHEMBL31554789 | 0.78 | BACE1 (0.57) | BACE1BACE2 | |
| SCHEMBL29388869 | 0.77 | GHSR (0.53) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352391-B2 | Compositions for inducing urinary voiding and defecation | DIGNIFY THERAPEUTICS, LLC (US) | 2022-06-07 | — | — | US | disclosed |