SCHEMBL29678518

SCHEMBL29678518

CN(C)c1ccc2c(c1)Oc1cc(N(C)C)ccc1C21OC(=O)c2cc(C(=O)ON3C(=O)CCC3=O)ccc21.CN(C)c1ccc2c(c1)Oc1cc(N(C)C)ccc1C21OC(=O)c2ccc(C(=O)ON3C(=O)CCC3=O)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.43
▸ HPGD P15428 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ CYP3A4 P08684 2/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ MEN1 O00255 3/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ MAPT P10636 3/20 0.42
▸ HTT P42858 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ USP2 O75604 1/20 0.42
▸ FTO Q9C0B1 9/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ BLM P54132 1/20 0.40
▸ SMAD3 P84022 1/20 0.40
▸ PRMT1 Q99873 1/20 0.40
▸ ACE2 Q9BYF1 1/20 0.40
▸ GSTP1 P09211 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20340166 0.97 MEN1 (0.41) ALDH1A1HPGDTDP1CYP3A4HIF1A
SCHEMBL11993611 0.96 ALDH1A1 (0.46) ALDH1A1HPGDTDP1CYP3A4HIF1A
SCHEMBL29569825 0.96 ALDH1A1 (0.46) ALDH1A1HPGDTDP1CYP3A4HIF1A
SCHEMBL20967763 0.88 ALDH1A1 (0.39) ALDH1A1HPGDTDP1CYP3A4HIF1A
SCHEMBL29579867 0.88 FTO (0.55) ALDH1A1HPGDTDP1CYP3A4HSD17B10
SCHEMBL19360153 0.87 CYP3A4 (0.40) ALDH1A1HPGDTDP1CYP3A4HSD17B10
SCHEMBL29349733 0.86 MAPT (0.62) ALDH1A1HPGDTDP1CYP3A4HSD17B10
SCHEMBL31580193 0.85 FTO (0.55) ALDH1A1HPGDTDP1CYP3A4HSD17B10
SCHEMBL334086 0.85 FTO (0.55) ALDH1A1HPGDTDP1CYP3A4HSD17B10
SCHEMBL29383733 0.85 FTO (0.55) ALDH1A1HPGDTDP1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114755415-A Combined factor induced degradation type endothelial cell and method for treating hepatic fibrosis diseases 清华大学 2022-07-15 — — CN claimed
WO-2024237764-A9 PROBE FOR MEASURING CATHEPSIN K ACTIVITY AND COMPOSITION FOR DIAGNOSING BONE DISEASE COMPRISING SAME 고려대학교 산학협력단 2025-03-13 — — WO disclosed
WO-2024237764-A2 PROBE FOR MEASURING CATHEPSIN K ACTIVITY AND COMPOSITION FOR DIAGNOSING BONE DISEASE COMPRISING SAME 고려대학교 산학협력단 2024-11-21 — — WO disclosed
EP-4425179-A2 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE Life Technologies Corporation (US) 2024-09-04 — — EP disclosed
EP-3507603-B1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE LIFE TECHNOLOGIES CORP (US) 2024-03-06 — — EP disclosed
US-20240042062-A1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE Life Technologies Corporation (US) 2024-02-08 — — US disclosed
US-11865191-B2 Compositions and methods for enhanced fluorescence Life Technologies Corporation (US) 2024-01-09 — — US disclosed
WO-2022183370-A1 ELECTRIC CELL IMPEDANCE SENSING-BASED METHOD FOR ANTITUMOR MEDICAMENT SCREENING 北京大学 2022-09-09 — — WO disclosed
CN-114755415-A Combined factor induced degradation type endothelial cell and method for treating hepatic fibrosis diseases 清华大学 2022-07-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240042062-A1 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE ANXA5, HNRNPF, ANXA6 ALDH1A1 2920/4885HPGD 3776/4885TDP1 335/4885
US-11865191-B2 Compositions and methods for enhanced fluorescence ANXA5, HNRNPF, ANXA6 ALDH1A1 2920/4885HPGD 3776/4885TDP1 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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