Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11993611 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL29678518 | 0.96 | ALDH1A1 (0.43) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL20340166 | 0.93 | MEN1 (0.41) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL20967763 | 0.91 | ALDH1A1 (0.39) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL30064563 | 0.87 | FTO (0.56) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL29501272 | 0.87 | FTO (0.56) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL29995636 | 0.87 | FTO (0.56) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL164316 | 0.87 | FTO (0.56) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL22434375 | 0.85 | MAPT (0.63) | ALDH1A1HPGDTDP1CYP3A4MEN1 | |
| SCHEMBL29359210 | 0.85 | MAPT (0.63) | ALDH1A1HPGDTDP1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107746-A1 | COMPOSITIONS AND METHODS OF DETECTING AND TREATING THROMBOSIS AND VASCULAR PLAQUES | MICROVASCULAR THERAPEUTICS, LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-114364383-A | Compositions and methods for detecting and treating thrombosis and vascular plaque | 微脉管治疗有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-3980016-A1 | COMPOSITIONS AND METHODS OF DETECTING AND TREATING THROMBOSIS AND VASCULAR PLAQUES | Microvascular Therapeutics LLC (US) | 2022-04-13 | — | — | EP | disclosed |