Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MGAM | O43451 | 3/20 | 0.47 |
| ▸ | SI | P14410 | 3/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609016 | 0.88 | NR3C1 (0.48) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL946518 | 0.81 | MEN1 (0.52) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL29678908 | 0.80 | GPR84 (0.61) | GPR84GAAMGAMSIMGAM2 | |
| SCHEMBL29678756 | 0.80 | GAA (0.51) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL29678938 | 0.79 | GAA (0.50) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL29678809 | 0.78 | NR3C1 (0.46) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL29678900 | 0.77 | NR3C1 (0.46) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL29678752 | 0.75 | MAPT (0.52) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL11347248 | 0.75 | MAPT (0.42) | GPR84NR3C1GAAMGAMSI | |
| SCHEMBL28587999 | 0.74 | L3MBTL1 (0.62) | GPR84NR3C1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | claimed |
| WO-2022131722-A1 | NOVEL INDOLE DERIVATIVE, METHOD FOR PREPARING SAME, AND COMPOSITION FOR IMPROVING COGNITIVE FUNCTIONS COMPRISING SAME | (주)케이메디켐 | 2022-06-23 | — | — | WO | disclosed |