Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679126 | 0.92 | CTSL (0.58) | CTSLCTSBCTSSF2CASP1 | |
| SCHEMBL29679181 | 0.92 | CTSL (0.58) | CTSLCTSBCTSSF2CASP1 | |
| SCHEMBL18623602 | 0.87 | CTSB (0.72) | CTSLCTSBCTSSITGB3ITGA2B | |
| SCHEMBL22764775 | 0.87 | CTSB (0.72) | CTSLCTSBCTSSITGB3ITGA2B | |
| SCHEMBL4634963 | 0.87 | CTSB (0.72) | CTSLCTSBCTSSITGB3ITGA2B | |
| SCHEMBL31696719 | 0.87 | CTSB (0.72) | CTSLCTSBCTSSITGB3ITGA2B | |
| SCHEMBL29401021 | 0.87 | CTSB (0.72) | CTSLCTSBCTSSITGB3ITGA2B | |
| SCHEMBL29678933 | 0.87 | CTSL (0.58) | CTSLCTSBCTSSF2CASP1 | |
| SCHEMBL30927131 | 0.83 | MDM4 (0.49) | — | |
| SCHEMBL29221384 | 0.83 | MDM4 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003959-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | Bayer AS (NO) | 2022-06-01 | — | — | EP | disclosed |