Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.72 |
| ▸ | CTSS | P25774 | 2/20 | 0.72 |
| ▸ | CTSL | P07711 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.57 |
| ▸ | CPA1 | P15085 | 2/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22764775 | 1.00 | CTSB (0.72) | CTSBCTSSCTSLCASP1ITGB3 | |
| SCHEMBL18623602 | 1.00 | CTSB (0.72) | CTSBCTSSCTSLCASP1ITGB3 | |
| SCHEMBL29401021 | 1.00 | CTSB (0.72) | CTSBCTSSCTSLCASP1ITGB3 | |
| SCHEMBL31696719 | 1.00 | CTSB (0.72) | CTSBCTSSCTSLCASP1ITGB3 | |
| SCHEMBL29679334 | 0.87 | CTSL (0.58) | CTSBCTSSCTSLCASP1ITGB3 | |
| SCHEMBL479010 | 0.86 | TACR1 (0.68) | CTSBCTSSCTSLITGB3ITGA2B | |
| SCHEMBL219151 | 0.86 | TACR1 (0.68) | CTSBCTSSCTSLITGB3ITGA2B | |
| SCHEMBL220648 | 0.86 | TACR1 (0.68) | CTSBCTSSCTSLITGB3ITGA2B | |
| SCHEMBL7372270 | 0.86 | TACR1 (0.68) | CTSBCTSSCTSLITGB3ITGA2B | |
| SCHEMBL26661077 | 0.86 | TACR1 (0.68) | CTSBCTSSCTSLITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4425181-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | Bertis Inc (KR) | 2024-09-04 | — | — | EP | disclosed |
| WO-2024150132-A1 | LIGAND-DRUG CONJUGATES | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2024-07-18 | — | — | WO | disclosed |
| US-20240011979-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS INC. (KR) | 2024-01-11 | — | — | US | disclosed |
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023075435-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | 주식회사 베르티스 | 2023-05-04 | — | — | WO | disclosed |
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| WO-2022050529-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | ㈜베르티스 | 2022-03-10 | — | — | WO | disclosed |
| EP-1930021-A2 | Novel amide derivatives as growth hormone secretagogues | Kaken Pharmaceutical Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-20070149446-A1 | Tamandarin analogs and fragments thereof and methods of making and using | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CENTER FOR TECHNOLOGY TRANSFER (US) | 2007-06-28 | — | — | US | disclosed |
| US-7022677-B1 | Amide derivatives as growth hormone secretagogues | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| EP-0950046-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-10-20 | — | — | EP | disclosed |
| US-5959123-A | REACATING SUBSTITUTED AMINO ACID WITH 3-AMINO-4-SUBSTITUTED-AZETIDINE-2-ONE COMPOUND TO FORM 3, 4-DISUBSTITUTED-AZETIDINE-2-ONE COMPOUND; USEFUL FOR TREATING MUSCULAR DYSTROPHY, ARTHRITIS, VIRAL AND PARASITIC INFECTIONS | SYNPHAR LABORATORIES, INC. (CA) | 1999-09-28 | — | — | US | disclosed |
| WO-1998012176-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | disclosed |
| US-5652369-A | PROTEASE INHIBITOR | HOFFMANN-LA ROCHE INC. (US) | 1997-07-29 | — | — | US | disclosed |
| US-5620987-A | Amino acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1997-04-15 | — | — | US | disclosed |
| US-5554756-A | PROTEASE INHIBITOR | HOFFMANN-LA ROCHE INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5446161-A | Protease inhibitor, viricides | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0346847-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 1994-05-11 | — | — | EP | disclosed |
| US-5157041-A | Viricides | HOFFMANN-LA ROCHE INC. (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0346847-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149446-A1 | Tamandarin analogs and fragments thereof and methods of making and using | FOXM1, F3, RB1 | CTSB 743/4885CTSS 737/4885CTSL 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.