Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600244 | 0.75 | AKT1 (0.33) | — | |
| SCHEMBL5607080 | 0.69 | NPC1 (0.34) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL23630012 | 0.68 | NPC1 (0.31) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL3676942 | 0.68 | NPC1 (0.31) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL5712971 | 0.68 | NPC1 (0.31) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL13238426 | 0.67 | MAPT (0.39) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL2968787 | 0.67 | ACHE (0.31) | ACHE | |
| SCHEMBL29482315 | 0.67 | NPC1 (0.31) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL14574631 | 0.67 | — | — | |
| SCHEMBL13238425 | 0.65 | MAPT (0.39) | NPC1ALDH1A1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673464-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-28 | — | — | EP | claimed |
| WO-2005035553-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-04-21 | — | — | WO | claimed |
| US-9601726-B2 | Sealing material for secondary battery and sealing material composition for secondary battery | ZEON CORPORATION (JP) | 2017-03-21 | — | — | US | disclosed |
| US-20160289372-A1 | POLYMERIZABLE COMPOSITION, RESIN SHAPED ARTICLE, COMPOSITE, AND LAMINATE | ZEON CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| US-20150188099-A1 | SEALING MATERIAL FOR SECONDARY BATTERY AND SEALING MATERIAL COMPOSITION FOR SECONDARY BATTERY | ZEON CORPORATION (JP) | 2015-07-02 | — | — | US | disclosed |
| US-8722828-B2 | Process for continuous production of cycloolefin resins, and sheets or films thereof, using ring opening metathesis polymerization | ZEON CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| EP-2083032-B1 | POLYMERIZABLE COMPOSITION, CROSSLINKABLE RESIN, AND MANUFACTURE METHODS AND APPLICATIONS THEREOF | ZEON CORP (JP) | 2014-02-12 | — | — | EP | disclosed |
| EP-2620483-A1 | ADHESIVE FILM FOR ORGANIC ELECTROLYTE ACCUMULATOR DEVICES | Zeon Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2017308-B1 | OXYGEN-ABSORBING RESIN COMPOSITION | KURARAY CO (JP) | 2013-03-13 | — | — | EP | disclosed |
| US-8080623-B2 | Polymerizable composition, crosslinkable resin, and manufacture methods and applications thereof | ZEON CORPORATION (JP) | 2011-12-20 | — | — | US | disclosed |
| US-7771834-B2 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1990364-A1 | MOLDED CROSSLINKABLE-RESIN OBJECT, MOLDED CROSSLINKED-RESIN OBJECT, AND CROSSLINKED-RESIN/METAL LAMINATE | ZEON CORPORATION (JP) | 2008-11-12 | — | — | EP | disclosed |
| US-20080132477-A1 | Macrocyclic Compounds Useful as Bace Inhibitors | NOVARTIS AG (CH) | 2008-06-05 | — | — | US | disclosed |
| EP-1535941-B1 | PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS | ZEON CORP (JP) | 2007-09-12 | — | — | EP | disclosed |
| US-20070037946-A1 | Process for producing cycloolefin resin film and process for producing cycloolefin polymer sheet or film | ZEON CORPORATION (JP) | 2007-02-15 | — | — | US | disclosed |
| US-20060211809-A1 | Polymerizable composition and formed article using the same | ZEON CORPORATION (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060211834-A1 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1652885-A1 | POLYMERIZABLE COMPOSITION AND FORMED ARTICLE USING THE SAME | Zeon Corporation (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1589055-A1 | PROCESS FOR PRODUCING CYCLOOLEFIN RESIN FILM AND PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER SHEET OR FILM | Zeon Corporation (JP) | 2005-10-26 | — | — | EP | disclosed |
| EP-1535941-A1 | PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS | ZEON CORPORATION (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132477-A1 | Macrocyclic Compounds Useful as Bace Inhibitors | BACE1, BACE2, APP | NPC1 41/4885ALDH1A1 2631/4885MAPT 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.