Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317911 | 0.73 | DPP4 (0.34) | — | |
| SCHEMBL5616226 | 0.64 | — | — | |
| SCHEMBL13064167 | 0.55 | ALDH1A1 (0.54) | — | |
| SCHEMBL11741027 | 0.55 | MYC (0.48) | — | |
| SCHEMBL28899579 | 0.54 | MYC (0.58) | — | |
| SCHEMBL623217 | 0.54 | ALDH1A1 (0.38) | — | |
| SCHEMBL13019332 | 0.53 | SCN4A (0.36) | — | |
| SCHEMBL1133067 | 0.52 | MYC (0.56) | — | |
| SCHEMBL23003867 | 0.51 | POLB (0.46) | AKT2 | |
| SCHEMBL31264394 | 0.51 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403854-B2 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-02 | — | — | US | disclosed |
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-25 | — | — | US | disclosed |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-07-05 | — | — | US | disclosed |
| US-20040097745-A9 | Stereospecific disproportionation of 1,2-disubstituted hydrocarbons in the cis configuration, using metal compounds as catalysts; catalysis | GRUBBS ROBERT H (US) | 2004-05-20 | — | — | US | disclosed |
| US-20030100776-A1 | Allows for substitution of functional groups within the olefin without comprising efficiency of metathesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | OXER1, OSTC, OXSR1 | AKT1 1066/4885AKT2 934/4885AKT3 2141/4885 |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | OXER1, OSTC, OXSR1 | AKT1 1066/4885AKT2 934/4885AKT3 2141/4885 |
| US-20030100776-A1 | Allows for substitution of functional groups within the olefin without comprising efficiency of metathesis | OXER1, OSTC, SQLE | AKT1 2105/4885AKT2 1879/4885AKT3 2990/4885 |
| US-20040097745-A9 | Stereospecific disproportionation of 1,2-disubstituted hydrocarbons in the cis configuration, using metal compounds as catalysts; catalysis | OXER1, OSTC, DUOX1 | AKT1 2316/4885AKT2 1863/4885AKT3 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.