SCHEMBL5607080

SCHEMBL5607080

Cc1cc(C)c(N2[C]CN(c3c(C)cc(C)cc3C)C2=Cc2ccccc2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
TACR1 P25103 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13238426 0.79 MAPT (0.39) NPC1ALDH1A1MAPTHPGDRAB9A
SCHEMBL13238425 0.71 MAPT (0.39) NPC1ALDH1A1MAPTHPGDRAB9A
SCHEMBL2967977 0.69 NPC1 (0.32) NPC1ALDH1A1MAPTHPGDRAB9A
SCHEMBL28059372 0.68 TACR1 (0.33) NPC1ALDH1A1MAPTHPGDRAB9A
SCHEMBL2968787 0.67 ACHE (0.31)
SCHEMBL2882672 0.67 ALDH1A1 (0.33) NPC1ALDH1A1MAPTHPGDRAB9A
Hydrochloric Acid SCHEMBL3670747 0.66 ALDH1A1 (0.32) NPC1ALDH1A1MAPTHPGDRAB9A
SCHEMBL5712971 0.65 NPC1 (0.31) NPC1ALDH1A1MAPTHPGDRAB9A
SCHEMBL13238424 0.65 ALDH1A1 (0.38) NPC1ALDH1A1MAPTHPGDRAB9A
Hydrochloric Acid SCHEMBL3670743 0.64 CRHR1 (0.33) NPC1ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722828-B2 Process for continuous production of cycloolefin resins, and sheets or films thereof, using ring opening metathesis polymerization ZEON CORPORATION (JP) 2014-05-13 US disclosed
US-20070037946-A1 Process for producing cycloolefin resin film and process for producing cycloolefin polymer sheet or film ZEON CORPORATION (JP) 2007-02-15 US disclosed
EP-1589055-A1 PROCESS FOR PRODUCING CYCLOOLEFIN RESIN FILM AND PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER SHEET OR FILM Zeon Corporation (JP) 2005-10-26 EP disclosed