Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 10/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000685 | 0.78 | MET (0.64) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL13052998 | 0.76 | ALDH1A1 (0.52) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL13998685 | 0.76 | ALDH1A1 (0.59) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL23633328 | 0.76 | MET (0.45) | METPDE3BPDE3A | |
| SCHEMBL30402259 | 0.76 | MET (0.41) | MET | |
| SCHEMBL17544422 | 0.76 | MET (0.41) | MET | |
| SCHEMBL9867688 | 0.75 | SGMS2 (0.55) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL2244448 | 0.74 | NPC1 (0.58) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL13998715 | 0.73 | HPGD (0.57) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL23458473 | 0.73 | ALDH1A1 (0.53) | KDM4ENPC1ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006016-A2 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |