Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 5/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24532111 | 1.00 | MEN1 (0.61) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL29681249 | 0.83 | MAPT (0.57) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL24532143 | 0.83 | MAPT (0.57) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL2899405 | 0.78 | MEN1 (0.61) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL24532295 | 0.76 | MEN1 (0.55) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL29681119 | 0.76 | MEN1 (0.55) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL11706489 | 0.74 | MEN1 (0.47) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL4215471 | 0.73 | KMO (0.55) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL2899403 | 0.73 | MAPT (0.48) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL18394788 | 0.72 | KMO (0.51) | MEN1KMT2ATDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263535-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | Astrazeneca AB (SE) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022130270-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2022-06-23 | — | — | WO | disclosed |