Ethyl Curcumin

Ethyl Curcumin

SCHEMBL8965263

CCOc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OCC)c2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 4/20 1.00
APP P05067 6/20 0.73
MAPT P10636 3/20 0.73
BACE1 P56817 3/20 0.73
NFKB1 P19838 3/20 0.73
CYP2D6 P10635 2/20 0.73
CYP2C9 P11712 2/20 0.73
TSHR P16473 2/20 0.73
HSD17B10 Q99714 2/20 0.73
ABCB1 P08183 2/20 0.73
AKR1B1 P15121 2/20 0.73
MAOA P21397 2/20 0.73
MAOB P27338 2/20 0.73
ALDH1A1 P00352 2/20 0.73
HDAC3 O15379 2/20 0.73
HDAC1 Q13547 2/20 0.73
HDAC2 Q92769 2/20 0.73
HDAC6 Q9UBN7 2/20 0.73
ALOX5 P09917 2/20 0.73
MMP9 P14780 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Curcumin SCHEMBL8965258 1.00 TOP2A (1.00) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL27686673 0.94 TOP2A (0.89) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL29929626 0.94 TOP2A (0.89) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL1374497 0.94 TOP2A (0.89) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL2622443 0.93 TOP2A (0.87) TOP2AAPPMAPTBACE1NFKB1
Water SCHEMBL28118110 0.93 TOP2A (0.87) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL27211484 0.93 TOP2A (0.86) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL13953311 0.90 TOP2A (0.81) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL3857596 0.89 TOP2A (0.79) TOP2AAPPMAPTBACE1NFKB1
SCHEMBL3857593 0.89 TOP2A (0.79) TOP2AAPPMAPTBACE1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5334481-A Positive diazo quinone photoresist compositions containing antihalation compound CIBA-GEIGY CORPORATION (US) 1994-08-02 US claimed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP disclosed
US-5399463-A Process of photopatterning a substrate with a positive photoresist composition containing a diazoquinone photosensitizer CIBA-GEIGY CORPORATION (US) 1995-03-21 US disclosed
US-5334481-A Positive diazo quinone photoresist compositions containing antihalation compound CIBA-GEIGY CORPORATION (US) 1994-08-02 US disclosed
US-5110706-A Photoresists for highly reflective substrates JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-05-05 US disclosed
EP-0200129-B1 POSITIVE PHOTORESIST COMPOSITIONS CIBA-GEIGY AG (CH) 1992-02-05 EP disclosed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP disclosed
EP-0200129-A2 Positive photoresist compositions CIBA-GEIGY AG (CH) 1986-11-05 EP disclosed