Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24553904 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2CYP1B1 | |
| SCHEMBL29348960 | 0.77 | MBOAT4 (0.37) | KDM4EALDH1A1CYP1B1 | |
| SCHEMBL31637575 | 0.77 | MBOAT4 (0.37) | KDM4EALDH1A1CYP1B1 | |
| SCHEMBL6643942 | 0.74 | EPHX2 (0.42) | SMN1; SMN2CYP1B1 | |
| SCHEMBL2750287 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL29348893 | 0.73 | NPC1 (0.43) | — | |
| SCHEMBL31637550 | 0.73 | NPC1 (0.43) | — | |
| SCHEMBL7704422 | 0.73 | CYP1B1 (0.32) | CYP1B1 | |
| SCHEMBL539467 | 0.72 | — | — | |
| SCHEMBL31416644 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) | 2025-09-04 | — | — | US | disclosed |
| WO-2022127756-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | PACSIN2, CSNK1A1, CSNK1G3 | KDM4E 1708/4885ALDH1A1 4340/4885SMN1; SMN2 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.