Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723030 | 0.86 | MME (0.48) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL30455467 | 0.86 | MME (0.50) | MMEACECPA1ACE2ECE1 | |
| SCHEMBL30685327 | 0.86 | PDCD1LG2 (0.42) | MMEACECPA1ACE2ECE1 | |
| SCHEMBL30053138 | 0.84 | MME (0.49) | MMEACECPA1ACE2ECE1 | |
| SCHEMBL29778417 | 0.84 | ENPEP (0.48) | MMEACECPA1ACE2ENPEP | |
| SCHEMBL9437456 | 0.84 | ECE1 (0.55) | ECE1ENPEP | |
| SCHEMBL27313721 | 0.84 | ECE1 (0.55) | ECE1ENPEP | |
| SCHEMBL9437463 | 0.84 | ECE1 (0.55) | ECE1ENPEP | |
| SCHEMBL9506153 | 0.84 | ECE1 (0.55) | ECE1ENPEP | |
| SCHEMBL31514372 | 0.83 | EGFR (0.38) | ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4262752-A1 | CLASS OF BIOMATERIALS FOR PROMOTING LARGE BLOOD VESSEL GROWTH | Vanderbilt University (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022133309-A1 | CLASS OF BIOMATERIALS FOR PROMOTING LARGE BLOOD VESSEL GROWTH | VANDERBILT UNIVERSITY (US) | 2022-06-23 | — | — | WO | disclosed |