SCHEMBL30455467

SCHEMBL30455467

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nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.50
ACE P12821 1/20 0.50
CPA1 P15085 1/20 0.50
ACE2 Q9BYF1 1/20 0.50
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
PTGS2 P35354 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TERT O14746 1/20 0.39
PTGS1 P23219 1/20 0.38
GSTK1 Q9Y2Q3 1/20 0.38
ECE1 P42892 1/20 0.37
GLO1 Q04760 1/20 0.36
ENPEP Q07075 5/20 0.35
MMP8 P22894 1/20 0.34
NMT2 O60551 1/20 0.33
NMT1 P30419 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31462095 0.89 TERT (0.42) MMEACECPA1ACE2TERT
SCHEMBL30053138 0.87 MME (0.49) MMEACECPA1ACE2ALDH1A1
SCHEMBL30455334 0.86 ALDH1A1 (0.44) MMEACECPA1ACE2ALDH1A1
SCHEMBL10863330 0.86 CTSD (0.43) MMEACECPA1ACE2
SCHEMBL10863318 0.86 CTSD (0.43) MMEACECPA1ACE2
SCHEMBL29683079 0.86 MME (0.48) MMEACECPA1ACE2ALDH1A1
SCHEMBL29723030 0.86 MME (0.48) MMEACECPA1ACE2ALDH1A1
SCHEMBL4088259 0.85 TERT (0.46) MMEACECPA1ACE2TERT
SCHEMBL4088251 0.85 TERT (0.46) MMEACECPA1ACE2TERT
SCHEMBL29392897 0.85 ALDH1A1 (0.43) MMEACECPA1ACE2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120844-A1 COMPOSITION FOR MASS PROLIFERATING NATURAL KILLER CELLS, COMPRISING NOVEL PEPTIDE, AND METHOD FOR MASS PROLIFERATING NATURAL KILLER CELLS BY USING SAME 엔케이젠 주식회사 2023-06-29 WO claimed
WO-2023120844-A1 COMPOSITION FOR MASS PROLIFERATING NATURAL KILLER CELLS, COMPRISING NOVEL PEPTIDE, AND METHOD FOR MASS PROLIFERATING NATURAL KILLER CELLS BY USING SAME 엔케이젠 주식회사 2023-06-29 WO disclosed