SCHEMBL2968366

SCHEMBL2968366

Brc1cccc2c3c(ccc12)C=CC3

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.42
PARP1 P09874 1/20 0.38
AHR P35869 1/20 0.33
PRNP P04156 1/20 0.31
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2973126 0.79 MEN1 (0.33) PNMTPRNP
SCHEMBL2974474 0.78 TRPA1 (0.36) AHR
SCHEMBL31285053 0.78 TRPA1 (0.36) AHR
SCHEMBL31497107 0.74 HPRT1 (0.52) AHR
SCHEMBL12475251 0.74 HPRT1 (0.52) AHR
SCHEMBL30541938 0.74 HPRT1 (0.52) AHR
SCHEMBL30446008 0.74 HPRT1 (0.52) AHR
SCHEMBL4403403 0.74 MEN1 (0.34)
Charcoal, Activated SCHEMBL3299280 0.73 HPRT1 (0.50) AHR
SCHEMBL2972391 0.73 CYP3A4 (0.34) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 PNMT 2021/4885PARP1 2168/4885AHR 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.