SCHEMBL2973126

SCHEMBL2973126

Brc1cc2c(c3ccccc13)CC=C2

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PRNP P04156 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RCE1 Q9Y256 1/20 0.30
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12661097 0.81 PNMT (0.32) MEN1ALDH1A1PRNPMAPTHPGD
SCHEMBL2968366 0.79 PNMT (0.42) PRNPPNMT
SCHEMBL2959311 0.74 POLB (0.36) ALDH1A1
SCHEMBL4401562 0.73 MCL1 (0.38) MEN1ALDH1A1KMT2A
SCHEMBL1881213 0.70 MPL (0.41) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL2975974 0.70 CRHBP (0.46) ALDH1A1
SCHEMBL2973804 0.70 DHFR (0.36) ALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL2962525 0.70 CA12 (0.37) ALDH1A1
SCHEMBL2962673 0.69 PTGS1 (0.33) MEN1KMT2A
SCHEMBL2971800 0.69 MEN1 (0.33) MEN1ALDH1A1PRNPMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 MEN1 750/4885ALDH1A1 4332/4885PRNP 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.