SCHEMBL29684100

SCHEMBL29684100

COCCc1cccc(N)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.59
MAOA P21397 2/20 0.59
CYP19A1 P11511 1/20 0.57
CYP3A4 P08684 3/20 0.45
ALDH1A1 P00352 1/20 0.45
TAAR1 Q96RJ0 1/20 0.43
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
SIGMAR1 Q99720 2/20 0.42
TP53 P04637 1/20 0.41
ENPP2 Q13822 1/20 0.41
ABHD6 Q9BV23 1/20 0.40
MAPT P10636 2/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6678878 1.00 MAOB (0.59) MAOBMAOACYP19A1CYP3A4ALDH1A1
SCHEMBL6693503 0.85 MAOB (0.52) MAOBMAOACYP19A1CYP3A4ALDH1A1
SCHEMBL7901300 0.85 ENPP2 (0.46) ALDH1A1TAAR1SIGMAR1ENPP2TSHR
SCHEMBL7140180 0.80 MAOB (0.46) MAOBCYP19A1CYP3A4TAAR1RAB9A
SCHEMBL29436994 0.80 MAOB (0.86) MAOBMAOACYP19A1CYP3A4ALDH1A1
SCHEMBL2154372 0.80 MAOB (0.86) MAOBMAOACYP19A1CYP3A4ALDH1A1
SCHEMBL2865197 0.80 MAOB (0.59) MAOBMAOACYP19A1CYP3A4ALDH1A1
SCHEMBL30966755 0.80 LOXL2 (0.47) MAOBCYP3A4ALDH1A1TAAR1ENPP2
SCHEMBL29264560 0.80 LOXL2 (0.47) MAOBCYP3A4ALDH1A1TAAR1ENPP2
SCHEMBL1048793 0.80 TAAR1 (0.61) MAOBCYP3A4TAAR1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763346-B Compounds for inducing cartilage formation and application thereof 华东师范大学 2025-06-10 CN disclosed
CN-114763346-A Compound for inducing chondrogenesis and application thereof 华东师范大学 2022-07-19 CN disclosed