Salicylic Acid

Salicylic Acid

SCHEMBL29684178

O=C(O)c1ccccc1O.[Zn]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.95
KDM4E B2RXH2 6/20 0.95
HPGD P15428 6/20 0.95
SMN1; SMN2 Q16637 2/20 0.95
CA12 O43570 2/20 0.95
CA1 P00915 2/20 0.95
CA2 P00918 2/20 0.95
CA7 P43166 2/20 0.95
CA9 Q16790 2/20 0.95
CA14 Q9ULX7 2/20 0.95
HMGB1 P09429 1/20 0.95
CA4 P22748 1/20 0.95
CA6 P23280 1/20 0.95
NAPRT Q6XQN6 1/20 0.95
ALOX15 P16050 2/20 0.65
HSD17B10 Q99714 4/20 0.59
MAPT P10636 3/20 0.58
TSHR P16473 2/20 0.58
G6PD P11413 1/20 0.58
CASP7 P55210 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL28657645 1.00 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL134084 1.00 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL8160376 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL503705 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL28023737 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL28006175 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29606432 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL8433746 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29360246 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL1509155 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190792-A1 TOPICAL PREPARATIONS Epitheal Limited (IE) 2023-06-22 US claimed
EP-4117613-A1 TOPICAL PREPARATIONS Epitheal Limited (IE) 2023-01-18 EP claimed
US-12398280-B2 Curable coating material for non-impact printing TIGER COATINGS GMBH & CO. KG (AT) 2025-08-26 US disclosed
CN-119026337-A Wheat yield and nitrogen absorption efficiency comprehensive identification model, method and application 河南省农业科学院植物营养与资源环境研究所 2024-11-26 CN disclosed
CN-118578804-A Thermosensitive recording material 乐凯医疗科技有限公司 2024-09-03 CN disclosed
US-20240010859-A1 CURABLE COATING MATERIAL FOR NON-IMPACT PRINTING TIGER COATINGS GMBH & CO. KG (AT) 2024-01-11 US disclosed
EP-3596552-B1 CURABLE COATING MATERIAL FOR NON-IMPACT PRINTING TIGER COATINGS GMBH & CO KG (AT) 2024-01-10 EP disclosed
US-11787960-B2 Curable coating material for non-impact printing TIGER COATINGS GMBH & CO. KG (AT) 2023-10-17 US disclosed
US-20230190792-A1 TOPICAL PREPARATIONS Epitheal Limited (IE) 2023-06-22 US disclosed
CN-113845699-B Organic metal complex modified ammonium polyphosphate intumescent flame retardant and preparation method thereof 福建师范大学 2023-03-10 CN disclosed
EP-4117613-A1 TOPICAL PREPARATIONS Epitheal Limited (IE) 2023-01-18 EP disclosed
WO-2023280172-A1 TERMINAL-MODIFIED POLYESTER RESIN, COMPOSITION THEREOF, MOLDED ARTICLE, AND PREPARATION METHOD 东丽先端材料研究开发(中国)有限公司 2023-01-12 WO disclosed
US-11499061-B2 Curable coating material for non-impact printing TIGER COATINGS GMBH & CO. KG (AT) 2022-11-15 US disclosed
CN-114660267-A Wheat root system characteristic and method for determining response of wheat root system characteristic to rhizosphere soil enzyme activity 河南省农业科学院植物营养与资源环境研究所 2022-06-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190792-A1 TOPICAL PREPARATIONS SLC39A11, SLC30A5, SLC30A7 ALDH1A1 780/4885KDM4E 3307/4885HPGD 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.