Salicylic Acid

Salicylic Acid

SCHEMBL503705

O.O.O.O=C(O)c1ccccc1O.[Zn]

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.90
KDM4E B2RXH2 7/20 0.90
HPGD P15428 7/20 0.90
SMN1; SMN2 Q16637 3/20 0.90
CA12 O43570 1/20 0.90
CA1 P00915 1/20 0.90
CA2 P00918 1/20 0.90
HMGB1 P09429 1/20 0.90
CA4 P22748 1/20 0.90
CA6 P23280 1/20 0.90
CA7 P43166 1/20 0.90
CA9 Q16790 1/20 0.90
NAPRT Q6XQN6 1/20 0.90
CA14 Q9ULX7 1/20 0.90
ALOX15 P16050 2/20 0.62
HSD17B10 Q99714 4/20 0.57
MAPT P10636 4/20 0.56
TSHR P16473 2/20 0.56
G6PD P11413 1/20 0.56
CASP7 P55210 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL28006175 1.00 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29684178 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL28657645 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29440406 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL9691144 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL8599857 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL1079228 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL134084 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL8596622 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL3948773 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1486199-B1 Alcoholic aerosol deodorant composition containing zinc salicylate OREAL (FR) 2007-10-17 EP claimed
US-20050019288-A1 Alcohol-based aerosol deodorant composition comprising at lease one zinc salicylate or a derivative thereof L'OREAL S.A. (FR) 2005-01-27 US claimed
WO-2025089221-A1 COMPOSITION, MOLDED BODY, FILM, AND LAYERED STRUCTURE 三菱ケミカル株式会社 2025-05-01 WO disclosed
CN-116075568-B Color-changeable adhesive sheet 日东电工株式会社 2024-02-06 CN disclosed
CN-116583568-A Color-changeable adhesive sheet 日东电工株式会社 2023-08-11 CN disclosed
CN-116113674-A Color-changeable adhesive sheet 日东电工株式会社 2023-05-12 CN disclosed
CN-116075568-A Color-changeable adhesive sheet 日东电工株式会社 2023-05-05 CN disclosed
CN-116057144-A Color-changeable adhesive sheet 日东电工株式会社 2023-05-02 CN disclosed
WO-2022054633-A1 COLOR-CHANGEABLE ADHESIVE SHEET 日東電工株式会社 2022-03-17 WO disclosed
CN-102414878-B Electrode plate for nonaqueous electrolyte secondary battery, method for producing electrode plate for nonaqueous electrolyte secondary battery, and nonaqueous electrolyte secondary battery DAINIPPON PRINTING CO LTD 2014-06-18 CN disclosed
CN-102414876-B Electrode plate for non-aqueous electrolyte secondary battery, method for producing electrode plate for non-aqueous electrolyte secondary battery, and non-aqueous electrolyte secondary battery DAINIPPON PRINTING CO LTD 2014-06-18 CN disclosed
US-20060219294-A1 Oxide semiconductor electrode, dye-sensitized solar cell, and, method of producing the same DAI NIPPON PRINTING CO., LTD. 2006-10-05 US disclosed
CN-1841786-A Oxide semiconductor electrode, dye-sensitized solar cell, and method for producing same DAINIPPON PRINTING CO LTD (JP) 2006-10-04 CN disclosed
US-20050183769-A1 Method of producing substrate for dye-sensitized solar cell and dye-sensitized solar cell DAI NIPPON PRINTING CO., LTD. (JP) 2005-08-25 US disclosed
US-6918662-B2 Ink composition and inkjet recording method and apparatus using the ink composition RICOH COMPANY LIMITED (JP) 2005-07-19 US disclosed
US-20050019288-A1 Alcohol-based aerosol deodorant composition comprising at lease one zinc salicylate or a derivative thereof L'OREAL S.A. (FR) 2005-01-27 US disclosed
US-20040179066-A1 Ink composition and inkjet recording method and apparatus using the ink composition RICOH COMPANY LIMITED (JP) 2004-09-16 US disclosed
US-6730149-B2 COLORANT AND A SOLVENT; ZETA POTENTIAL BETWEEN THE COLORANT AND GLASS, SILICON, SILICON OXIDE, TITANIUM OXIDE, CHROMIUM OXIDE, TITANIUM NITRIDE, SILICON NITRIDE, ZIRCONIUM AND POLYIMIDE IS FROM 0--50 MV AT A PH OF 6.5-11.5 RICOH COMPANY LIMITED (JP) 2004-05-04 US disclosed
US-20030010252-A1 Ink composition and inkjet recording method and apparatus using the ink composition RICOH COMPANY LIMITED (JP) 2003-01-16 US disclosed
US-5696169-A CONTAINING A ZINC COMPOUND AND HINOKITIOL OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050019288-A1 Alcohol-based aerosol deodorant composition comprising at lease one zinc salicylate or a derivative thereof ADH5, ADH1A, ADH1C ALDH1A1 6/4885KDM4E 3170/4885HPGD 1271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.