Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.83 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.81 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | XDH | P47989 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | KDM1A | O60341 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028368 | 1.00 | PTPN1 (0.83) | PTPN1CYP19A1TP53CYP3A4XDH | |
| SCHEMBL15756384 | 0.92 | PTPN1 (0.84) | PTPN1CYP19A1TP53CYP3A4XDH | |
| SCHEMBL31028359 | 0.91 | PTPN1 (1.00) | PTPN1CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL2966440 | 0.91 | PTPN1 (1.00) | PTPN1CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29684675 | 0.91 | PTPN1 (1.00) | PTPN1CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL27183317 | 0.87 | CYP19A1 (0.75) | PTPN1CYP19A1TP53CYP3A4XDH | |
| SCHEMBL17362369 | 0.86 | PTPN1 (0.79) | PTPN1CYP19A1TUBB4ATUBBYES1 | |
| Butin SCHEMBL68554 | 0.85 | CYP19A1 (1.00) | PTPN1CYP19A1TP53CYP3A4MAPT | |
| Liquirtigenin SCHEMBL718387 | 0.85 | CYP19A1 (0.89) | PTPN1CYP19A1CYP3A4MAPTNPC1 | |
| Butin SCHEMBL29929348 | 0.85 | CYP19A1 (1.00) | PTPN1CYP19A1TP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | claimed |
| US-20180135029-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2018-05-17 | — | — | US | claimed |
| US-9877946-B2 | Method for treating, managing, inhibiting, or preventing obesity | Research & Business Foundation Sungkyunkwan University (KR) | 2018-01-30 | — | — | US | claimed |
| EP-2963109-B1 | Process for the biotechnological production of flavanonglycoside dihydrochalcones | SYMRISE AG (DE) | 2017-09-06 | — | — | EP | claimed |
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) | 2017-03-30 | — | — | US | claimed |
| US-9549908-B2 | Composition for inducing differentiation into beige and brown adipocytes and method of inducing the same | Research & Business Foundation Sungkyunkwan University, Ltd. (KR) | 2017-01-24 | — | — | US | claimed |
| WO-2016050656-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2016-04-07 | — | — | WO | claimed |
| EP-3002335-A1 | Process for the biotechnological production of flavonoids | Symrise AG (DE) | 2016-04-06 | — | — | EP | claimed |
| US-20150374643-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2015-12-31 | — | — | US | claimed |
| US-10435673-B2 | Method for the biotechnological production of flavonoids | SYMRISE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| US-10435673-B2 | Method for the biotechnological production of flavonoids | SYMRISE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | disclosed |
| US-20180135029-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2018-05-17 | — | — | US | disclosed |
| US-20180135029-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2018-05-17 | — | — | US | disclosed |
| EP-2692729-A1 | Method for the biotechnological manufacture of dihydrochalcones? | Symrise AG (DE) | 2014-02-05 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2253226-A1 | Use of hydroxyflavone derivatives for modifying taste | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | Leibniz-Institut fur Pflanzenbiochemie (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | FABP4, PLIN1, PRDM7 | PTPN1 2153/4885CYP19A1 1244/4885TP53 4705/4885 |
| US-20150374643-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | FABP4, PLIN1, PRDM7 | PTPN1 2153/4885CYP19A1 1244/4885TP53 4705/4885 |
| US-20100292175-A1 | USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION | TAS2R50, TAS2R60, TAS2R30 | PTPN1 2982/4885CYP19A1 3419/4885TP53 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.