Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.71 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.68 |
| ▸ | TUBB | P07437 | 1/20 | 0.68 |
| ▸ | YES1 | P07947 | 1/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028359 | 1.00 | PTPN1 (1.00) | PTPN1CYP19A1POLBCYP1A1CYP1A2 | |
| SCHEMBL29684675 | 1.00 | PTPN1 (1.00) | PTPN1CYP19A1POLBCYP1A1CYP1A2 | |
| SCHEMBL15756384 | 0.92 | PTPN1 (0.84) | PTPN1CYP19A1POLBTUBB4ATUBB | |
| SCHEMBL31028368 | 0.91 | PTPN1 (0.83) | PTPN1CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL2968419 | 0.91 | PTPN1 (0.83) | PTPN1CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL17362369 | 0.88 | PTPN1 (0.79) | PTPN1CYP19A1TUBB4ATUBBYES1 | |
| SCHEMBL5084433 | 0.87 | PTPN1 (0.77) | PTPN1CYP19A1POLBCYP1A1CYP1A2 | |
| SCHEMBL5084437 | 0.87 | PTPN1 (0.77) | PTPN1CYP19A1POLBCYP1A1CYP1A2 | |
| Liquirtigenin SCHEMBL718387 | 0.85 | CYP19A1 (0.89) | PTPN1CYP19A1TUBB4ATUBBYES1 | |
| Butin SCHEMBL68554 | 0.85 | CYP19A1 (1.00) | PTPN1CYP19A1POLBCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | claimed |
| US-20180135029-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2018-05-17 | — | — | US | claimed |
| US-9877946-B2 | Method for treating, managing, inhibiting, or preventing obesity | Research & Business Foundation Sungkyunkwan University (KR) | 2018-01-30 | — | — | US | claimed |
| EP-2963109-B1 | Process for the biotechnological production of flavanonglycoside dihydrochalcones | SYMRISE AG (DE) | 2017-09-06 | — | — | EP | claimed |
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) | 2017-03-30 | — | — | US | claimed |
| US-9549908-B2 | Composition for inducing differentiation into beige and brown adipocytes and method of inducing the same | Research & Business Foundation Sungkyunkwan University, Ltd. (KR) | 2017-01-24 | — | — | US | claimed |
| WO-2016050656-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2016-04-07 | — | — | WO | claimed |
| EP-3002335-A1 | Process for the biotechnological production of flavonoids | Symrise AG (DE) | 2016-04-06 | — | — | EP | claimed |
| US-20150374643-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2015-12-31 | — | — | US | claimed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-10857082-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2020-12-08 | — | — | US | disclosed |
| US-7767661-B2 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767661-B2 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | FABP4, PLIN1, PRDM7 | PTPN1 2153/4885CYP19A1 1244/4885POLB 4459/4885 |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | PTPN1 1357/4885CYP19A1 203/4885POLB 928/4885 |
| US-20150374643-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | FABP4, PLIN1, PRDM7 | PTPN1 2153/4885CYP19A1 1244/4885POLB 4459/4885 |
| US-10857082-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | PTPN1 1357/4885CYP19A1 203/4885POLB 928/4885 |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | PTPN1 1357/4885CYP19A1 203/4885POLB 928/4885 |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | TYR, MAOA, CYP51A1 | PTPN1 3131/4885CYP19A1 221/4885POLB 797/4885 |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | PTPN1 1357/4885CYP19A1 203/4885POLB 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.