Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357838 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2AEPHX1HPGDLTA4H | |
| SCHEMBL6138081 | 0.84 | HPGD (0.46) | ALDH1A1KMT2AEPHX1HPGDLTA4H | |
| SCHEMBL6138080 | 0.84 | HPGD (0.46) | ALDH1A1KMT2AEPHX1HPGDLTA4H | |
| SCHEMBL15906239 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AEPHX1HPGDLTA4H | |
| SCHEMBL9220946 | 0.80 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KMT2AMEN1LTA4H | |
| SCHEMBL6136293 | 0.79 | LTA4H (0.55) | KMT2AEPHX1HPGDLTA4HEPHX2 | |
| SCHEMBL6136289 | 0.79 | LTA4H (0.55) | KMT2AEPHX1HPGDLTA4HEPHX2 | |
| SCHEMBL7437533 | 0.78 | HPGD (0.57) | KMT2AEPHX1HPGDLTA4HEPHX2 | |
| SCHEMBL8829934 | 0.78 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1KMT2AEPHX1HPGD | |
| SCHEMBL9829897 | 0.78 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1KMT2AEPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962959-B1 | NEUROPEPTIDE-2 RECEPTOR-AGONISTS | HOFFMANN LA ROCHE (CH) | 2012-03-14 | — | — | EP | disclosed |