Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254816 | 1.00 | PKM (0.42) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL29688354 | 0.86 | PKM (0.41) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL20254625 | 0.86 | PKM (0.41) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL20254710 | 0.85 | SMN1; SMN2 (0.41) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL29688572 | 0.85 | SMN1; SMN2 (0.41) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL29688577 | 0.81 | ALDH1A1 (0.39) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL20255000 | 0.81 | ALDH1A1 (0.39) | PKMTSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL20254958 | 0.81 | PKM (0.47) | PKMTSHRSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL29688741 | 0.81 | PKM (0.47) | PKMTSHRSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL29688636 | 0.80 | PKM (0.37) | PKMTSHRSMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267959-B | Imidazo [1,5-A ] pyrazine derivatives as PI3K delta inhibitors | 百济神州有限公司 | 2022-05-27 | — | — | CN | disclosed |