Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254958 | 1.00 | PKM (0.47) | PKMALDH1A1DYRK1AMAPTPOLB | |
| SCHEMBL20254816 | 0.81 | PKM (0.42) | PKMALDH1A1DYRK1AMAPTPOLB | |
| SCHEMBL29688382 | 0.81 | PKM (0.42) | PKMALDH1A1DYRK1AMAPTPOLB | |
| SCHEMBL29688354 | 0.80 | PKM (0.41) | PKMALDH1A1DYRK1AMAPTTSHR | |
| SCHEMBL20254625 | 0.80 | PKM (0.41) | PKMALDH1A1DYRK1AMAPTTSHR | |
| SCHEMBL20254710 | 0.78 | SMN1; SMN2 (0.41) | PKMALDH1A1DYRK1AMAPTPOLB | |
| SCHEMBL29688572 | 0.78 | SMN1; SMN2 (0.41) | PKMALDH1A1DYRK1AMAPTPOLB | |
| SCHEMBL14753937 | 0.76 | TSHR (0.46) | ALDH1A1MAPTPOLBTSHRHTT | |
| SCHEMBL29688577 | 0.74 | ALDH1A1 (0.39) | PKMALDH1A1DYRK1APOLBTSHR | |
| SCHEMBL20255000 | 0.74 | ALDH1A1 (0.39) | PKMALDH1A1DYRK1APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267959-B | Imidazo [1,5-A ] pyrazine derivatives as PI3K delta inhibitors | 百济神州有限公司 | 2022-05-27 | — | — | CN | disclosed |