Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135313 | 1.00 | HPGD (0.38) | HPGDALDH1A1MAPK1MEN1CYP1A2 | |
| SCHEMBL20135515 | 0.89 | ALDH1A1 (0.40) | ALDH1A1MAPK1MEN1CYP1A2CYP2C9 | |
| SCHEMBL29688956 | 0.89 | ALDH1A1 (0.40) | ALDH1A1MAPK1MEN1CYP1A2CYP2C9 | |
| SCHEMBL20135045 | 0.84 | LMNA (0.44) | ALDH1A1MEN1CYP2C19KMT2AKDM4E | |
| SCHEMBL29689005 | 0.84 | LMNA (0.44) | ALDH1A1MEN1CYP2C19KMT2AKDM4E | |
| SCHEMBL20135490 | 0.83 | MEN1 (0.41) | ALDH1A1MAPK1MEN1CYP1A2CYP2C9 | |
| SCHEMBL20135021 | 0.82 | ALDH1A1 (0.38) | HPGDALDH1A1MAPK1MEN1CYP1A2 | |
| SCHEMBL20135719 | 0.82 | TDP1 (0.37) | ALDH1A1KDM4ELMNAHTTADAMTS5 | |
| SCHEMBL29688395 | 0.82 | TDP1 (0.37) | ALDH1A1KDM4ELMNAHTTADAMTS5 | |
| SCHEMBL20135076 | 0.80 | ADAM17 (0.37) | ALDH1A1MAPK1MEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |