Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135358 | 1.00 | TSHR (0.33) | TSHRBCHECES1AKR1B1MMP2 | |
| SCHEMBL20135280 | 0.81 | LCK (0.35) | TSHRMMP2MAPTNPSR1ADAM17 | |
| SCHEMBL20135013 | 0.73 | ADAMTS5 (0.35) | AKR1B1ADAM17ADAMTS5 | |
| SCHEMBL15973908 | 0.67 | LMNA (0.46) | AKR1B1MMP2MMP3MMP8MMP14 | |
| SCHEMBL1505362 | 0.63 | MAPT (0.52) | TSHRGAASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL31483694 | 0.62 | MAPT (0.50) | TSHRSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL20836401 | 0.62 | MAPT (0.50) | TSHRSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL15031974 | 0.62 | MAPT (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20134891 | 0.61 | MMP14 (0.40) | AKR1B1MMP2MMP8MMP14MMP17 | |
| SCHEMBL4232196 | 0.60 | CYP2C9 (0.55) | AKR1B1MMP2MMP3GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |