Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915780 | 1.00 | PTGS2 (0.48) | PTGS2PTGS1LMNAHPGDTDP1 | |
| SCHEMBL1960131 | 0.83 | LMNA (0.45) | PTGS2PTGS1LMNAHPGDTDP1 | |
| SCHEMBL5723333 | 0.80 | LMNA (0.45) | PTGS2PTGS1LMNAHPGDTDP1 | |
| SCHEMBL20101689 | 0.79 | LMNA (0.52) | PTGS2LMNAHPGDALDH1A1KMT2A | |
| SCHEMBL31717974 | 0.79 | KMT2A (0.50) | PTGS2LMNATDP1ALDH1A1KMT2A | |
| SCHEMBL6139521 | 0.79 | PTGS2 (0.69) | PTGS2PTGS1LMNAHPGDERN1 | |
| SCHEMBL14070022 | 0.77 | LMNA (0.64) | LMNAHPGDTDP1ALDH1A1KMT2A | |
| SCHEMBL19153574 | 0.75 | PTPRC (0.56) | PTGS2PTGS1LMNAHPGDTDP1 | |
| SCHEMBL12722842 | 0.73 | PTGS2 (0.48) | PTGS2PTGS1HPGDALDH1A1CYP1A2 | |
| SCHEMBL1664233 | 0.72 | TP53 (0.48) | PTGS2PTGS1ALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773354-B | Simple synthesis method of Trisphaeridine | 武汉理工大学 | 2023-03-24 | — | — | CN | claimed |
| CN-114773354-A | Simple synthesis method of Trisphaeridine | 武汉理工大学 | 2022-07-22 | — | — | CN | claimed |
| CN-116003320-A | Preparation method of phenanthridine compound | 武汉理工大学深圳研究院 | 2023-04-25 | — | — | CN | disclosed |
| CN-114773354-B | Simple synthesis method of Trisphaeridine | 武汉理工大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-114773354-B | Simple synthesis method of Trisphaeridine | 武汉理工大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-114773354-A | Simple synthesis method of Trisphaeridine | 武汉理工大学 | 2022-07-22 | — | — | CN | disclosed |