Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 6/20 | 0.35 |
| ▸ | CES2 | O00748 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783027 | 0.89 | CES1 (0.40) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL217738 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL5575821 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1506925 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL5840662 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL6577114 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL489856 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL6561911 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1925873 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL5993484 | 0.88 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12104038-B2 | Silica reinforced rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-10-01 | — | — | US | disclosed |
| US-11708475-B2 | Method for preparing modified filler, compositions and articles containing same | PPG INDUSTRIES OHIO, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230174743-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | THE GOODYEAR TIRE & RUBBER COMPANY | 2023-06-08 | — | — | US | disclosed |
| EP-4190589-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | The Goodyear Tire & Rubber Company (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230033274-A1 | METHOD FOR PREPARING MODIFIED FILLER, COMPOSITIONS AND ARTICLES CONTAINING SAME | PPG INDUSTRIES OHIO, INC. (US) | 2023-02-02 | — | — | US | disclosed |
| EP-4077525-A1 | METHOD FOR PREPARING MODIFIED FILLER, COMPOSITIONS AND ARTICLES CONTAINING SAME | PPG Industries Ohio Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| US-20220204722-A1 | SILICA REINFORCED RUBBER | GOODYEAR TIRE & RUBBER COMPANY, THE | 2022-06-30 | — | — | US | disclosed |