Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993381 | 1.00 | KDM4E (0.52) | KDM4ENPC1TP53RAB9ALMNA | |
| SCHEMBL31609343 | 0.88 | KDM4E (0.70) | KDM4ENPC1TP53RAB9ALMNA | |
| SCHEMBL322178 | 0.88 | KDM4E (0.70) | KDM4ENPC1TP53RAB9ALMNA | |
| SCHEMBL1456807 | 0.87 | GOT1 (0.46) | KDM4ENPC1TP53RAB9ALMNA | |
| SCHEMBL30792004 | 0.87 | GOT1 (0.46) | KDM4ENPC1TP53RAB9ALMNA | |
| SCHEMBL29442588 | 0.87 | GOT1 (0.46) | KDM4ENPC1TP53RAB9ALMNA | |
| Water SCHEMBL3749603 | 0.86 | KDM4E (0.67) | KDM4ENPC1TP53RAB9ALMNA | |
| Hydrogen Sulfide SCHEMBL3749800 | 0.86 | KDM4E (0.67) | KDM4ENPC1TP53RAB9ALMNA | |
| Oxazole SCHEMBL27790750 | 0.83 | KDM4E (0.38) | KDM4ENPC1TP53RAB9ALMNA | |
| SCHEMBL17631434 | 0.82 | GRM5 (0.40) | KDM4ENPC1TP53RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728175-A | Antigen binding protein constructs and uses thereof | 神话治疗股份有限公司 | 2022-07-08 | — | — | CN | disclosed |