Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.38 |
| ▸ | VCP | P55072 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
| ▸ | FLT4 | P35916 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925546 | 1.00 | DGAT1 (0.38) | DGAT1VCPDHODHKDM4EGLA | |
| SCHEMBL28733870 | 0.88 | VCP (0.42) | DGAT1VCPSIRT7FLT1KDR | |
| SCHEMBL22925677 | 0.88 | VCP (0.42) | DGAT1VCPSIRT7FLT1KDR | |
| SCHEMBL29696312 | 0.88 | VCP (0.42) | DGAT1VCPSIRT7FLT1KDR | |
| SCHEMBL22925766 | 0.84 | ALOX5 (0.39) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL22925740 | 0.84 | ALOX5 (0.39) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL29696308 | 0.84 | ALOX5 (0.39) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL22925730 | 0.83 | VCP (0.44) | DGAT1VCPSIRT7FLT1KDR | |
| SCHEMBL29621023 | 0.83 | VCP (0.44) | DGAT1VCPSIRT7FLT1KDR | |
| SCHEMBL28939255 | 0.83 | VCP (0.44) | DGAT1VCPSIRT7FLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | claimed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |