Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 4/20 | 0.35 |
| ▸ | FLT4 | P35916 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925756 | 1.00 | NPSR1 (0.43) | NPSR1LIPEFLT1FLT4KDR | |
| SCHEMBL29696304 | 0.91 | IMPDH2 (0.43) | NPSR1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL22926080 | 0.91 | IMPDH2 (0.43) | NPSR1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL22925755 | 0.83 | IMPDH2 (0.38) | LIPEFLT1FLT4KDRIMPDH2 | |
| SCHEMBL29620887 | 0.83 | IMPDH2 (0.38) | LIPEFLT1FLT4KDRIMPDH2 | |
| SCHEMBL22925796 | 0.83 | IMPDH2 (0.39) | NPSR1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL29696291 | 0.83 | IMPDH2 (0.39) | NPSR1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL28733796 | 0.81 | PPARD (0.41) | NPSR1IMPDH2GSK3BPDE2APPARD | |
| SCHEMBL22925905 | 0.81 | PPARD (0.41) | NPSR1IMPDH2GSK3BPDE2APPARD | |
| SCHEMBL22925757 | 0.81 | NPSR1 (0.40) | NPSR1FLT1KDRVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |