Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.39 |
| ▸ | VCP | P55072 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 6/20 | 0.38 |
| ▸ | FLT4 | P35916 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925796 | 1.00 | IMPDH2 (0.39) | IMPDH2VCPCYP11B1CYP11B2FLT1 | |
| SCHEMBL29696304 | 0.89 | IMPDH2 (0.43) | IMPDH2VCPFLT1FLT4KDR | |
| SCHEMBL22926080 | 0.89 | IMPDH2 (0.43) | IMPDH2VCPFLT1FLT4KDR | |
| SCHEMBL22925794 | 0.84 | IMPDH2 (0.41) | IMPDH2VCPCYP11B1CYP11B2FLT1 | |
| SCHEMBL29696282 | 0.84 | IMPDH2 (0.41) | IMPDH2VCPCYP11B1CYP11B2FLT1 | |
| SCHEMBL22925756 | 0.83 | NPSR1 (0.43) | IMPDH2VCPFLT1FLT4KDR | |
| SCHEMBL29696317 | 0.83 | NPSR1 (0.43) | IMPDH2VCPFLT1FLT4KDR | |
| SCHEMBL22925782 | 0.81 | ALOX5 (0.42) | VCPFLT1FLT4KDRNPSR1 | |
| SCHEMBL29696295 | 0.81 | ALOX5 (0.42) | VCPFLT1FLT4KDRNPSR1 | |
| SCHEMBL22926050 | 0.79 | NPSR1 (0.39) | IMPDH2VCPFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |