Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.55 |
| ▸ | REN | P00797 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030564 | 0.90 | REN (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL7272881 | 0.85 | ACE (0.55) | ACERENKDM4EF2LMNA | |
| SCHEMBL11031456 | 0.82 | ACE (0.54) | ACELMNALTA4HACE2 | |
| SCHEMBL19817050 | 0.81 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL13019815 | 0.81 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL10658196 | 0.81 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL7271630 | 0.80 | ACE (0.50) | ACERENKDM4EF2LMNA | |
| SCHEMBL11221776 | 0.80 | ACE (0.55) | ACELMNAACE2 | |
| SCHEMBL11031153 | 0.80 | ACE (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL10912494 | 0.80 | ACE (0.47) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522855-B2 | Methods and kits for identifying thrombus origin and optimizing post-ischemic event treatment | TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) | 2026-01-13 | — | — | US | disclosed |
| CN-115962786-A | Traffic path recommendation method and system | 中国人民解放军火箭军工程大学 | 2023-04-14 | — | — | CN | disclosed |
| US-20220298539-A1 | METHODS AND KITS FOR IDENTIFYING THROMBUS ORIGIN AND OPTIMIZING POST-ISCHEMIC EVENT TREATMENT | TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) | 2022-09-22 | — | — | US | disclosed |
| EP-4004560-A1 | METHODS AND KITS FOR IDENTIFYING THROMBUS ORIGIN AND OPTIMIZING POST-ISCHEMIC EVENT TREATMENT | TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) | 2022-06-01 | — | — | EP | disclosed |