Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028937 | 1.00 | SIGMAR1 (0.53) | SIGMAR1DNM1MAPTSMN1; SMN2P2RX3 | |
| SCHEMBL31120931 | 0.93 | POLB (0.48) | SIGMAR1MAPTMEN1KMT2AMAOA | |
| SCHEMBL28402672 | 0.88 | SIGMAR1 (0.41) | SIGMAR1DNM1MAPTSMN1; SMN2HTT | |
| SCHEMBL5999998 | 0.85 | SIGMAR1 (0.48) | SIGMAR1DNM1MAPTSMN1; SMN2P2RX3 | |
| SCHEMBL6755578 | 0.85 | SIGMAR1 (0.48) | SIGMAR1DNM1MAPTSMN1; SMN2P2RX3 | |
| SCHEMBL6755616 | 0.85 | SIGMAR1 (0.48) | SIGMAR1DNM1MAPTSMN1; SMN2P2RX3 | |
| SCHEMBL31073662 | 0.82 | SIGMAR1 (0.49) | SIGMAR1DNM1MAPTSMN1; SMN2P2RX3 | |
| SCHEMBL11127173 | 0.82 | SIGMAR1 (0.54) | SIGMAR1DNM1MAPTSMN1; SMN2PSEN1 | |
| SCHEMBL751367 | 0.82 | SIGMAR1 (0.54) | SIGMAR1DNM1MAPTSMN1; SMN2PSEN1 | |
| SCHEMBL3823482 | 0.82 | SIGMAR1 (0.54) | SIGMAR1DNM1MAPTSMN1; SMN2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521934-B | Hyperbranched electroluminescent polymer, and polymerization monomer, preparation method and application thereof | 华南理工大学 | 2022-07-26 | — | — | CN | disclosed |