SCHEMBL5999998

SCHEMBL5999998

CC(C)CCCC(C)CCn1c2ccc(Br)cc2c2cc(Br)ccc21

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.48
DNM1 Q05193 5/20 0.46
MAPT P10636 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
P2RX3 P56373 1/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 2/20 0.37
BAX Q07812 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PSEN1 P49768 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
TSPO P30536 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6755616 1.00 SIGMAR1 (0.48) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL6755578 1.00 SIGMAR1 (0.48) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL4261394 0.87 SIGMAR1 (0.39) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL4267813 0.85 SIGMAR1 (0.38) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL28028937 0.85 SIGMAR1 (0.53) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL29696476 0.85 SIGMAR1 (0.53) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL4261398 0.81 DNM1 (0.34) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL6018351 0.79 SIGMAR1 (0.45) SIGMAR1DNM1MAPTSMN1; SMN2P2RX3
SCHEMBL4267819 0.79 DNM1 (0.33) SIGMAR1DNM1MAPTSMN1; SMN2PPARG
SCHEMBL31120931 0.79 POLB (0.48) SIGMAR1MAPTPOLBTSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060073357-A1 Carbazole compounds and use of such compounds in organic electroluminiscent devices KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2006-04-06 US disclosed
EP-1594939-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES Koninklijke Philips Electronics N.V. (NL) 2005-11-16 EP disclosed
WO-2004072205-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-08-26 WO disclosed
US-20040087761-A1 Novel polycarbazole and process for preparation thereof NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) 2004-05-06 US disclosed