Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 4/20 | 0.36 |
| ▸ | CDK8 | P49336 | 4/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706244 | 0.84 | HSD17B10 (0.44) | KDM4AKDM4BKDM5CKDM5BGAA | |
| SCHEMBL28804353 | 0.76 | CDK5 (0.43) | PARP1L3MBTL1CSNK1A1TYRO3DYRK1B | |
| SCHEMBL30665045 | 0.76 | CDK5 (0.43) | PARP1L3MBTL1CSNK1A1TYRO3DYRK1B | |
| SCHEMBL4100623 | 0.74 | ATR (0.34) | CCNCCDK8KDM4AKDM4BKDM5C | |
| SCHEMBL29696588 | 0.73 | BRAF (0.40) | GDAPARP1CCNCCDK8BRAF | |
| SCHEMBL17541171 | 0.71 | CSNK1A1 (0.45) | GDAPARP1CCNCCDK8GAA | |
| SCHEMBL1747899 | 0.71 | KDM4A (0.37) | GDAKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL1056425 | 0.71 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL14034284 | 0.70 | GDA (0.41) | GDAPARP1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL13348562 | 0.70 | GDA (0.41) | GDAPARP1GAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | disclosed |