Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454974 | 1.00 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5462258 | 0.90 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5463490 | 0.89 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL27957392 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5452268 | 0.86 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL23674627 | 0.77 | LMNA (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL30100786 | 0.77 | LMNA (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL28017046 | 0.77 | SMN1; SMN2 (0.78) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL28571267 | 0.75 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL2487702 | 0.75 | LMNA (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533729-B | Tetrazole-substituted quinolinone derivative and preparation method and application thereof | 盐城工学院 | 2022-07-26 | — | — | CN | disclosed |