Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463490 | 0.86 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL28454974 | 0.86 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL29696608 | 0.86 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5466499 | 0.85 | MEN1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5462258 | 0.85 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5460787 | 0.83 | RXFP1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5456985 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5461187 | 0.81 | DRD2 (0.45) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5462219 | 0.81 | PDE4A (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL5324569 | 0.77 | HTR6 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287699-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | ALDH1A1 1759/4885SMN1; SMN2 2454/4885MEN1 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.