SCHEMBL29696975

SCHEMBL29696975

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nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.44
CTSD P07339 2/20 0.44
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
ECE1 P42892 3/20 0.42
MME P08473 5/20 0.40
TGFBR1 P36897 1/20 0.38
ACE P12821 1/20 0.37
CPA1 P15085 1/20 0.37
ACE2 Q9BYF1 1/20 0.37
DPP4 P27487 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30068583 1.00 BACE1 (0.44) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL30184223 0.97 BACE1 (0.43) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL31169711 0.91 BACE1 (0.51) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL29440233 0.89 MME (0.48) BACE1CTSDMMEACECPA1
SCHEMBL9852025 0.89 MME (0.44) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL29697058 0.89 MME (0.44) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL9852027 0.89 MME (0.44) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL29517369 0.89 MME (0.44) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL29867829 0.88 MME (0.47) BACE1CTSDPDCD1LG2CD274ECE1
SCHEMBL29889514 0.88 PDCD1LG2 (0.55) BACE1CTSDPDCD1LG2CD274ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 BACE1 307/4885CTSD 251/4885PDCD1LG2 1212/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 BACE1 307/4885CTSD 251/4885PDCD1LG2 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.