Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307914 | 0.91 | BACE1 (0.45) | MMECTSDBACE1 | |
| SCHEMBL30797948 | 0.90 | GNPAT (0.46) | MMELTA4HCTSDBACE1ACE | |
| SCHEMBL29874706 | 0.90 | MME (0.52) | MMELTA4HCTSDBACE1GNPAT | |
| SCHEMBL29696975 | 0.89 | BACE1 (0.44) | MMECTSDBACE1ACECPA1 | |
| SCHEMBL30068583 | 0.89 | BACE1 (0.44) | MMECTSDBACE1ACECPA1 | |
| SCHEMBL30552861 | 0.89 | MME (0.41) | MMELTA4HCTSDBACE1ACE | |
| SCHEMBL3341838 | 0.88 | LTA4H (0.49) | MMELTA4HACECPA1ACE2 | |
| SCHEMBL10494263 | 0.88 | LTA4H (0.49) | MMELTA4HACECPA1ACE2 | |
| SCHEMBL2807590 | 0.88 | LTA4H (0.49) | MMELTA4HACECPA1ACE2 | |
| SCHEMBL4957790 | 0.88 | LTA4H (0.49) | MMELTA4HACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251157-A1 | IgM-MEDIATED RECEPTOR CLUSTERING AND CELL MODULATION | MAYO FOUND MEDICAL EDUCATION & RES (US) | 2022-08-11 | — | — | US | disclosed |
| US-11274131-B2 | IgM-mediated receptor clustering and cell modulation | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2022-03-15 | — | — | US | disclosed |