SCHEMBL29697013

SCHEMBL29697013

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nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.51
ACE P12821 5/20 0.51
CPA1 P15085 1/20 0.51
ACE2 Q9BYF1 1/20 0.51
NPY1R P25929 1/20 0.49
NPY2R P49146 1/20 0.49
NPY4R P50391 1/20 0.49
FOLH1 Q04609 1/20 0.49
SLC6A2 P23975 1/20 0.49
BACE1 P56817 1/20 0.48
OPRD1 P41143 2/20 0.48
OPRM1 P35372 1/20 0.48
KISS1R Q969F8 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30252365 1.00 MME (0.51) MMEACECPA1ACE2NPY1R
SCHEMBL31406596 0.93 KISS1R (0.53) MMEACECPA1ACE2NPY1R
SCHEMBL675899 0.92 KISS1R (0.50) ACENPY1RNPY2RNPY4ROPRD1
SCHEMBL675898 0.92 KISS1R (0.50) ACENPY1RNPY2RNPY4ROPRD1
SCHEMBL29738689 0.91 BACE1 (0.55) NPY1RNPY2RNPY4RBACE1KISS1R
SCHEMBL29528212 0.91 OPRD1 (0.57) MMEACECPA1ACE2NPY1R
SCHEMBL30799540 0.91 OPRD1 (0.54) BACE1OPRD1OPRM1KISS1R
SCHEMBL29657465 0.91 BACE1 (0.56) MMEACECPA1ACE2BACE1
SCHEMBL31721890 0.91 PDCD1LG2 (0.53) MMEACECPA1ACE2NPY1R
SCHEMBL30407854 0.90 OPRD1 (0.57) SLC6A2BACE1OPRD1OPRM1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 MME 286/4885ACE 3899/4885CPA1 199/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 MME 286/4885ACE 3899/4885CPA1 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.